In Mexico, tequila is often drunk straight. It is popular in some regions to drink fine tequila with a side of sangrita—a sweet, sour and spicy drink made from a blend of vegetable and fruit juices and spices which is unique to each Tequila house.  Equal-sized shots of tequila and sangrita are sipped alternately, without salt or lime.

Outside Mexico, a single shot of tequila is often served with salt and a slice of lime. This is called "tequila cruda" and is sometimes referred to as "training wheels," "lick-sip-suck," or "lick-shoot-suck" (referring to the way in which the combination of ingredients is consumed )

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